Literaturempfehlungen zur Ozontherapie

Ein praktisches Handbuch (Renate Viebahn-Hänsler und Olga Sonia Léon Fernàndez) 
3. Auflage , 2018;   ISBN 978-3-934181-05-2  
Das von SAGOS empfohlene Standardwerk!


Ozone Therapy 
 Oxidative Conditioning, Basis for its Clinical Effectiveness
Prof. Olga Sonia Leon Fernandez PHD
Englisch, 202 Seiten, ODREI  Publishers 2014
 ISBN 978-3-934181-03-7

The book gives information about the mechanisms of action, which justify the therapeutical effectiveness of medical ozone. 
It explains why that specific therapeutical concept is effective in so many illnesses. „The ozonetherapy is a therapeutical alternative that has demonstrated its clinical effectiveness in the treatment of a wide variety of physiopathological states apparently not related to each other. Examples of them are the vascular dysfunctions, the infectious process, rheumatoid arthritis, disc hernia, diabetes, convulsions, ischemic syndrome and others“

Guide to Using Medical Ozone 
 Therapeutic Foundations and Indications
The most complete work written in Spanish
Adriana Schwartz et al., AEPROMO, 2011, 315 p. + XVIII + 11 p. Color plates. 
ISBN: 978-84-615-2244-6

The book gives information about the properties of the ozone, its mechanisms of action, forms and methods of application. In its pages you will find instructions to properly implement this valuable therapy as recommended by the authors, experts in research and clinical practice of ozone. 

... und 7 Übersichtsarbeiten:

1.   Aktuelle Publikation von Dezember 2011: 
Mechanisms of Action Involved in Ozone Therapy: 
„Is healing induced via a mild oxidative stress?“
siehe  Link  HIER

2.   Scientific and Medical Aspects of Ozone Therapy         Bocci, 2006
Scientific and medical aspects of ozone therapy. State of the Art
11 Seiten, davon 2 Seiten mit 64 Referenzen; in englischer Sprache. 
Eine sehr lesenswerte Standortbestimmung mit folgenden Kapiteln / Auszügen: 

Einleitung; Was ist Ozon und wozu verwenden wir es?; Was geschieht mit Ozon bei Kontakt mit Körperflüssigkeiten?; Was sind die biologischen Wirkungen von ROS und LOP?; Anwendungsweise von Ozon; Wann ist Ozontherapie indiziert?; Hyperbare Sauerstofftherapie und Ozontherapie; Zusammenfassung und Ausblick. 

3.  Oxygen-Ozone Therapy in Medicine: An Update
Blood Purif. 2009 Sep 10;28(4):373-376. [Epub ahead of print]
Bocci V, Di Paolo N.
Department of Physiology, University of Siena, Siena, Italy
Oxygen-ozone therapy, initially started as an empirical approach, has now reached a stage where most of the biological mechanisms of action of ozone have been clarified, showing that they are in the realm of orthodox biochemistry, physiology and pharmacology. 

4. Meilensteine des Medizinischen Ozons
Medizinisches Ozon im Blickpunkt der Kritik. 15. Ozon-Weltkongress 2001 in London, Eröffnungsvortrag (deutsche Version); 
PDF-Download unter:

5. The Current Satus of Ozone Therapy                         Empiric Developments and Basic Research
Forsch.Komplementärmed. 1998; 30 Seiten, 72 Referenzen.
PDF-Download unter:

6. OZONE A NEW MEDICAL DRUG                                       von Velio Bocci 
Prof. Velio Bocci ist Physiologe in Siena, Italien. 
Er hat viele Forschungsarbeiten über Ozontherapie durchgeführt und veröffentlicht.
Springer Verlag 2005; ISBN 1-4020-3139-4 (HB); ISBN 1-4020-3140-8 (e-book);  EUR 159.00 

Zitat: „Ozone can be considered a pleiotropic*) bioregulator because it generates a reaction cascade of several compounds  responsible for a variety of biologigcal effects.“ 

*) pleios=viel; trop= Wirkung, Richtung; 
Pleiotropy describes the genetic effect of a single gene on multiple phenotypic traits. 
The underlying mechanism is that the gene codes for a product that is for example used by various cells, or has a signalling function on various targets

This book clarifies that, in the often nebulous field of natural medicine, the biological bases of ozone therapy are totally in line with classic biochemical, physiological and pharmacological knowledge. 

Ozone is an oxidising molecule, a sort of superactive oxygen, which, by reacting with blood components, generates a number of chemical messengers responsible for activating crucial biological functions such as oxygen delivery, immune activation, release of hormones and induction of antioxidant enzymes, which is an exceptional property for correcting the chronic oxidative stress present in atherosclerosis, diabetes, infections and cancer. Moreover ozone therapy, by inducing nitric oxide synthase, may mobilize endogenous stem cells, which will promote regeneration of ischaemic tissues. 

The description of these phenomena offers the first comprehensive picture for understanding how ozone works and why, when properly used as a real drug within the therapeutic range, not only does not procure adverse effects but yields a feeling of wellness. 

Half of the book describes the value of ozone therapy in several diseases, particularly cutaneous infections and vascular diseases where ozone really behaves as a "wonder" drug. The book has been written for clinical researchers, physicians and ozonetherapists but also for the layman or the patient interested in this therapy. 

7. Tropospheric Ozone Toxicity vs.                                         Usefulness of ozone therapy.                                           von Velio Bocci 
Bocci VA 
Arch Med Res Feb 2007; 38(2) :265-7
Volltext beim Verlag erhältlich | Zitat herunterladen

Department of Physiology, University of Siena, Siena, Italy.

There is a general consensus that continuous inhalation of air polluted with ozone is detrimental for the lungs and vital organs. Even if the concentration of tropospheric ozone is slightly above the tolerated dose, toxicity ensues owing to the cumulative dose inhaled for months. 
However, in medicine ozone is used as a real drug and a precise concentration and therapeutic dosage must be calibrated against the antioxidant capacity of blood. As ozone reacts with blood, it generates pharmacological messengers such as H2O2 and lipid oxidation products (LOPs). These activate several biochemical pathways in blood cells, which after reinfusion are responsible for therapeutic activities lasting several days. Neither acute nor chronic toxicity has been registered

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Aktualisierte Literaturliste (publiziert durch Ozonosan Iffenzheim) von Januar 2014

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