CLINICAL ASPECT OF 02/03 IN RHEUMATIC DISEASES.


Z. Fahmy.
Augusta-Klinik, 55543 Bad Kreuznach, Germany.

Among the disorders collectively named as rheumatism, progressive chronic polyarthritis constitutes a great problem, not only as regards to the frequency of its occurrence (1-2 % of the population), but also as regards its most effective therapy. Apart from non-medication (or physical) therapy methods, long-term antirheumatics, or so called basis therapeutics, represent the only medicaments known to have effects on the pathological processes involved, going beyond a symptomatic influence, contrary to the non-steroid antirheumatics and the corticoids. In medical ozone research over the recent year, we have arrived at results with confirm the necessity for therapeutical application of an ozone-oxygene gas mixture, not only clinically, but also biochemically.

 

CORRELATION OF PLASMA INTERLEUKIN 1 LEVELS WITH DISEASE ACTIVITY IN RHEUMATOID ARTHRITIS WITH AND WITHOUT OZONE.

Z. Fahmy.
Augusta-Klinik, 55543 Bad Kreuznach, Germany.

The mean plasma level of interleukin 1 beta was significantly higher in 51 patients with rheumatoid arthritis (RA) than in 21 rheumatoid arthritis patients treated with ozone, as control group of similar age in both groups. Plasma IL-1 beta correlated positively with Ritchie joint index, pain score, and erythrocyte sedimentation rate and correlated negatively with haemoglobin concentration. These results support the idea that IL-1 beta has a central role in the phatogenesis of RA and the ozone has influenced in the concentration level of IL-1 beta.

IMMUNOLOGICAL FINDINGS IN THE PERIPHERAL BLOOD AND IN THE SYNOVIAL FLUID AFTER INTRAARTICULAR OZONE INJECTIONS IN RHEUMATOID ARTHRITIS.

Z. Fahmy.
Augusta-Klinik, 55543 Bad Kreuznach, Germany.

The aim of this pilot study is to find the influence that 02/03 exerts in the cytokines in peripheral blood and in synovial fluid. In this study we have two groups of classical rheumatoid arthritis. One group treated with 02/03 (major haemotherapy and intraarticular 02/03 injections), the other group without 02/03. We find there are significant changes with 02/03 (granulocytes and other cell population).